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Enzymes such as Dipeptidyl Peptidase-4 (DPP-4) and Neutral Endopeptidase (NEP) contribute to this process, yielding inactive biological fragments (23)(30) Semaglutide, Serum, and tissue proteases metabolize the polypeptide into amino acids, clearing it from the system and preventing accumulation (23)(21)

The analysis involved 29 sequences, and all positions containing gaps and missing data were removed

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